Technology Offers Chemistry

Identification of "Defense Primers" using OTR – Boosting the innate immune response for agro & pharma applications

The method developed at RWTH Aachen University enables the identification of immune primers using OTR monitoring in a new and very efficient way. Areas of application include plant protection, but also the pharmaceutical industry (preventive medical immune system priming).



Glass perfectly covered or bonded – novel lamination of thin polymer layers on structured surfaces

With this new process, structured substrates can be laminated without damaging or narrowing the underlying functional structure. The method is simple and cost-effective, suitable for different materials and allows a free choice of precisely adjustable and stackable layer thicknesses.



Determining a person’s biological age, using a sophisticated set of biomarkers

The biological age can reliably be determined with this innovative biomarker set consisting of 30 newly identified biomarkers with a high correlation to the aging process.



Bio-based, non-isocyanate shape memory polyhydroxyurethanes (SMPHUs) with programmable and switchable shapes

As part of a project funded by the Baden-Wuerttemberg Stiftung gGmbH, scientists at the University of Freiburg succeeded in developing an innovative, relatively simple process that enables sustainable, less dangerous and preferably solvent-free production of smart poly(beta-hydroxy)urethanes (PHUs) using bio-based components.
These shape memory polyhydroxyurethanes (SMPHU) can be used for a wide range of applications – from moldings, coatings and fibers to films, actuators and components used in medical engineering.



Highly conductive pastes for printable electronic applications and devices

At the Karlsruhe Institute of Technology (KIT), a new platform concept for the formulation of highly conductive, printable pastes has been developed. Corresponding pastes are free of polymeric or other non-volatile stabilizers and rheology control agents. Nevertheless, rheological properties like low-shear viscosity and yield stress can be adjusted in a wide range. Thus sedimentation /aggregation is prohibited and long-term stability can be guaranteed even for suspensions of high density particles (e.g. Ag, Ni). Also full control of the application behavior in many different printing/coating operations is furnished.



Efficient method for ‘Chain Multiplication’ of unsaturated fatty acids - synthesis of ultra long-chain compounds

Currently, there are only very few, costly synthetic routes for the production of ultra long-chain compounds, as they typically rely on tedious multistep reaction sequences.
At the University of Konstanz (in the course of a project funded by the Baden-Württemberg Foundation), an iterative method (any multiplication factor) has been developed that produces terminally functionalized, purely aliphatic compounds through a ‘Chain Doubling’ approach starting from common monounsaturated fatty acids. All starting materials are readily available and the individual steps of the catalytic process do not involve further reagents. Moreover, there is only a small amount of byproducts which makes the method very efficient.
The method described here can be applied for the production of high-melting, purely aliphatic polymers and nanocrystals.



Efficient and low-cost water purification based on innovative, functional membrane coating

In cooperation with Italian partners, Karlsruhe University of Applied Sciences recently developed a new type of anti-fouling coating on membranes with scalable retention to improve the quality of purified water while reducing the costs involved in cleaning, maintaining and replacing the membranes. Pore sizes and thus separation efficiency and chemical properties of the novel PBM coated membrane surface can be individually adjusted to the composition of the water to be purified. The PBM coated ultrafiltration membranes were successfully tested in membrane bioreactor (MBR) systems using real wastewater.



Direct programmable detection of epigenetic cytosine modifications in DNA using TALEs

Epigenetic modifications at the 5-position of cytosine in DNA provide important clues for diseases such as neurological disorders and a range of cancers. Scientists at the University of Konstanz have now developed a method which allows the direct detection, i.e. without prior chemical modification of the DNA sample, of the epigenetic modification status in the 5-position of cytosine (such as 5mC and 5hmC) in any user-defined sequence. It is a simple and reliable method with high resolution and can be combined with a multitude of detection methods. Detection both in vivo and in vitro is possible.



Novel cathode material for lithium-sulfur batteries and lithium-ion batteries

At Aalen University, a novel composite material and a production process thereof was developed which makes the structural and material separation of current collector and cathode material unnecessary. The cathode material can be manufactured and formed in a continuous single stage electroplating process without the need to add binding material and electrically conductive particles. The proportion of active material in the cathode can thus be increased. Moreover, the mechanical stability and the efficiency of Li-Ion cells and Li-Sulfur cells improve.



Cellulose-based micro- and super-microfibres produced as continuous yarn suitable for weaving and knitting

A novel direct-wet-spin process was developed and patented by the German Institute of Textile Chemistry and Chemical Fibres (ITCF) in Denkendorf, which allows for the first time the cost-efficient production of micro- and supermicro-fibres of less than 0.1-0.5 dtex (fibre surface about 1 - 4 m2/g) from cellulose and cellulose-2.5-acetate in the form of a continuous fibre in a single-step process. The fibres can be stored as staple fibres or wound up as a continuous fibre for further processing.



New macro-porous ceramics and glass filters from capillary suspensions

Researchers at the Karlsruhe Institute of Technology (KIT) have developed a novel, simple and potentially cost-saving production process for macro-porous ceramics. The process is based on the use of the capillary effect in a three phase suspension of nano- to micro-sized solid particulates. In this manner, it is possible to fabricate ceramics and polymer foams with macro-pores of diameter 50 nm or greater and narrow pore size distribution.



Novel hybrid fluorescent nanoparticles with outstandingly high light intensity

Researchers at the Karlsruhe Institute of Technology (KIT) have successfully developed low-cost, fluorescent dyes with especially high light intensities. These inorganic–organic hybrid dyes can be synthesized easily and isolated, stored and redispersed in common solvents (ethanol/water). They can be excited using blue light (UV or blue light from LED) and emit depending on their composition in the blue, green, red or infrared spectrum. Preferred are applications in the field of medical diagnostic and therapeutic, advertising material and safety equipment (fluorescent marker).

In the field of biology and medicine the advantage of the inventive fluorescent dyes are their sufficient biocompatibility and highly specific signals, that don´t overlap with auto fluorescence of organs, cells and organelles. Thus the hybrid fluorescent dyes represent attractive alternatives to the widely used semiconductor quantum dots and rare earth doted oxides or fluorides.